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I am on carfilzomib and pomalyst and if anyone else is on the same medication what side effects they may have.

A MyMyelomaTeam Member asked a question 💭
Tifton, GA

I had SCT in December of 2024 using my cells.

June 30, 2025
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MyMyelomaTeam

Carfilzomib (Kyprolis) is a proteasome inhibitor that works by interfering with cancer cells' waste-removal systems. Common side effects of these medications can include:

• Nausea and vomiting
• Anemia (low red blood cells)
• Low platelet counts that may cause bleeding issues
• Low white blood cell counts
• Hair loss
• Show Full Answer

Carfilzomib (Kyprolis) is a proteasome inhibitor that works by interfering with cancer cells' waste-removal systems. Common side effects of these medications can include:

• Nausea and vomiting
• Anemia (low red blood cells)
• Low platelet counts that may cause bleeding issues
• Low white blood cell counts
• Hair loss
• Potential cardiovascular effects Pomalidomide (Pomalyst) belongs to the immunomodulatory drug class and may cause:

• Bleeding problems
• Infections
• Anemia
• Nerve damage
• Blood clots (your doctor may recommend aspirin or blood thinners)
• Fatigue
• Nausea

It's important to report any side effects to your healthcare team as they can help manage these symptoms and adjust treatment if needed.

June 30, 2025
A MyMyelomaTeam Member

I was on them back in 2017. I did not get a response from tis combination, but it certainly doesn't mean you won't. I think it's a good idea to check your blood pressure every day at home. Carfilzomib (Kyprolis) can make your blood pressure go up. I've been on the Pomalyst since early 2017. Fatigue is my biggest issue. I also have to stay on top of constipation. I'm getting neuropathy. Joel Andrews at Emory has me taking alpha lipoic acid 600 mg and super b complex. You might want to ask about taking them.

June 30, 2025

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