Induction therapy for myeloma can cause a range of long-term side effects. Not every person experiences all of them — individual responses vary depending on the specific drug combination used, overall health, and other factors.
Here are some of the more common long-term side effects to be aware of:
- Peripheral neuropathy Show Full Answer
Induction therapy for myeloma can cause a range of long-term side effects. Not every person experiences all of them — individual responses vary depending on the specific drug combination used, overall health, and other factors.
Here are some of the more common long-term side effects to be aware of:
- Peripheral neuropathy — nerve damage causing pain, tingling, numbness, or weakness in the hands and feet (especially associated with bortezomib)
- Anemia — low red blood cell levels leading to fatigue and shortness of breath
- Neutropenia — low white blood cell counts, increasing infection risk
- Thrombocytopenia — low platelet levels, which can cause bleeding problems
- Bone pain — from myeloma activity in the bones and bone marrow
- Fatigue — persistent tiredness that can linger after treatment
- Weakened bones — particularly with long-term corticosteroid use (like dexamethasone) As for how many myeloma patients experience these — it's hard to give one number since it depends on the drug regimen. For example, at least 20% of people on lenalidomide report side effects, while neuropathy is more closely tied to bortezomib use.
The encouraging news is that many side effects can be managed or improve after treatment ends. Always keep your care team informed about any symptoms — they can adjust dosing or recommend supportive treatments to help protect your quality of life.
August 16
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