Induction therapy for myeloma typically involves a combination of drugs — most commonly daratumumab, lenalidomide, bortezomib, and dexamethasone. Each of these can bring its own set of side effects, so it's worth knowing what to watch for.
Here are the most commonly reported side effects:
- Fatigue — feeling unusually Show Full Answer
Induction therapy for myeloma typically involves a combination of drugs — most commonly daratumumab, lenalidomide, bortezomib, and dexamethasone. Each of these can bring its own set of side effects, so it's worth knowing what to watch for.
Here are the most commonly reported side effects:
- Fatigue — feeling unusually tired, even with rest
- Nausea and vomiting
- Diarrhea or constipation
- Low blood cell counts — which can increase infection risk, cause anemia, or lead to bleeding issues
- Peripheral neuropathy — tingling, numbness, or pain in the hands and feet
- Fever
- Back pain
- Easy bruising or bleeding
- Loss of appetite
Corticosteroids like dexamethasone can also suppress the immune system and weaken bones over time, though these effects typically ease once treatment ends.
It's really important to be open with the care team about any side effects experienced — even ones that seem minor. Many side effects can be managed with additional medications or adjustments to the treatment plan, which can make a big difference in quality of life.
July 26
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