Connect with others who understand.

  •   Learn from expert-reviewed resources
  •   Real advice from people who’ve been there
  •   People who understand what you’re going through
Sign Up Log In
All Resources Treatments A-Z Personal Assistant Help Center Crisis
Powered By
Real members of MyMyelomaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

How many others experience tiredness/sleepiness in the AM? Not every morning but lately it's happening more. I'm on Maintenance with Rev.

A MyMyelomaTeam Member asked a question 💭
Mansfield, MA
July 20
 · 
Reactions

Answer Summary

Members on Revlimid maintenance resonated with the question about morning tiredness, widely agreeing that fatigue is a very real and common... Read more

Members on Revlimid maintenance resonated with the question about morning tiredness, widely agreeing that fatigue is a very real and common side effect that can build over time. Several members shared practical strategies including short catnaps, light exercise or walks, and sleep studies that led to CPAP or APAP machines, which helped some members wake up without headaches. A recurring theme was the importance of listening to your body, resting when needed, and searching resources like 'Cancer Treatment-Related Fatigue' to better understand what many are going through.

A MyMyelomaTeam Member

Even after a good night's sleep, I could close my eyes and nap by 10:30am. I don't usually, but only because I fight through it. Fatigue is, most definitely, a side effect. I've also been told that Revlimid has an accumulative effect. Next month will be 9 years for me.

July 20
MyMyelomaTeam

Morning tiredness is very common with myeloma — you're definitely not alone in this. Fatigue is actually one of the most frequently reported concerns among people with myeloma, and it can be influenced by several factors at once.

Being on Revlimid (lenalidomide) maintenance can contribute to fatigue as a side effect. Other Show Full Answer

Morning tiredness is very common with myeloma — you're definitely not alone in this. Fatigue is actually one of the most frequently reported concerns among people with myeloma, and it can be influenced by several factors at once.

Being on Revlimid (lenalidomide) maintenance can contribute to fatigue as a side effect. Other common contributors include:

- Anemia — very common with myeloma and can cause persistent tiredness
- Poor sleep quality — pain, neuropathy, or anxiety can disrupt overnight rest, leaving you groggy in the morning
- Emotional stress — the ongoing weight of a myeloma diagnosis can quietly drain energy
- Nutrition and hydration — if either is off, fatigue can worsen One MyMyelomaTeam member shared, "I never realized how exhausting it is to do laundry — I keep having to stop and rest."

Since the tiredness is increasing, it's worth mentioning to your oncologist. They can check for things like anemia or consider whether your current medication timing might be adjusted. Sometimes a small tweak, like taking Rev at night instead of the morning, can make a real difference in how you feel during the day.

July 20
A MyMyelomaTeam Member

Yes I always rest when needed.

July 23
A MyMyelomaTeam Member

We are bombarding our bodies with chemical poisons. It's all bound to catch up with us. Sometimes I'm in the middle of something, and I just have to keep going. But if possible, I take a short catnap to help revive me.

July 20
A MyMyelomaTeam Member

Fatigue is common from the low red blood cell counts, stomach upset, nightly insomnia or poor sleep. Side effects of both multiple myeloma and Revlimid. I conquer them with exercise , or walks, but that isn’t necessarily for all. A short nap is okay, but extended sleep will cause more insomnia.

July 20

Related Questions

View All

Living with Linalidomide (Revlimid) What Is Your Experience and How to Overcome

A MyMyelomaTeam Member asked a question 💭
want to share a little update about my journey. Recently I went for a CT scan of my lungs, and today the doctor explained the results to me. They found some changes in my left lung compared to before. There are areas where the lung lining looks thicker, and a small mass in the lower part of the left lung has grown a bit since my last scan. Because of these changes, the doctors want to do another test called a bronchoscopy, where they use a small camera to look inside the airways and take samples to understand it better. Hearing all this was not easy for me. It made me emotional because it feels like one thing after another. But at the same time, I am thankful that I am already under medical care and the doctors are taking steps to find out exactly what
January 23

Lower Heart rate or Daytime Sleepiness?

A MyMyelomaTeam Member asked a question 💭
want to share a little update about my journey. Recently I went for a CT scan of my lungs, and today the doctor explained the results to me. They found some changes in my left lung compared to before. There are areas where the lung lining looks thicker, and a small mass in the lower part of the left lung has grown a bit since my last scan. Because of these changes, the doctors want to do another test called a bronchoscopy, where they use a small camera to look inside the airways and take samples to understand it better. Hearing all this was not easy for me. It made me emotional because it feels like one thing after another. But at the same time, I am thankful that I am already under medical care and the doctors are taking steps to find out exactly what
August 4

What drug/treatment is a chemotherapy, if not Revlimid?

A MyMyelomaTeam Member asked a question 💭
Hollis AK
December 28, 2025

The Power of Mentoring Others With Myeloma
Multiple Myeloma Maintenance Therapy: 6 Facts
How Long Can Remission Last in Multiple Myeloma? Longest, Average, and More