MyMyelomaTeam

Dealing with Revlimid-related diarrhea is a real challenge — and you're definitely not alone in this. It's one of the most common side effects, and it can sometimes show up quite late, even 17 to 24 months after starting treatment. The most important first step is to talk to your oncologist before trying anything new, even Show Full Answer

Dealing with Revlimid-related diarrhea is a real challenge — and you're definitely not alone in this. It's one of the most common side effects, and it can sometimes show up quite late, even 17 to 24 months after starting treatment. The most important first step is to talk to your oncologist before trying anything new, even over-the-counter remedies. Here are some strategies that may help, always with your doctor's guidance:

Medications
- Loperamide (Imodium) has helped some MyMyelomaTeam members
- Cholestyramine (a bile acid sequestrant) has also worked for some
- One MyMyelomaTeam member shared that Pepto-Bismol unexpectedly did the trick for them

Dietary Changes
- Eat smaller, more frequent meals
- Choose foods like white rice, well-cooked vegetables, yogurt, lean meats, and smooth peanut butter
- Reduce fatty foods
- Eat foods rich in sodium and potassium to replace lost nutrients

Stay Hydrated
- Aim for 8–12 cups of water or clear fluids daily
- Broth and clear liquids can help after a bout of diarrhea If diarrhea becomes severe, your doctor may consider adjusting or pausing your Revlimid dose. Never make that call on your own — always loop in your care team first.

 AI-generated responses are not a substitute for medical advice. These services are not intended to diagnose, treat, or cure any condition or disease. Always ask your doctor about specific health concerns.

Multiple Myeloma and Bowel Problems: Diarrhea, Constipation, and More