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Real members of MyMyelomaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Is lower back something we should expect continuously.

A MyMyelomaTeam Member asked a question 💭
West Monroe, LA

I have 0 m- spike on urine and bleed test the past year. Some light- chain in bone marrow 6 or 7% in small areas of bone marrow. can or is this reason for continuous lower pain?

May 28
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MyMyelomaTeam

Having a 0 M-spike on both urine and blood tests for the past year is genuinely encouraging news — that means the myeloma is well controlled right now. However, lower back pain can still be a real and ongoing issue even when M-protein levels are undetectable.

Here's why lower back pain can persist:

- Previous bone damage Show Full Answer

Having a 0 M-spike on both urine and blood tests for the past year is genuinely encouraging news — that means the myeloma is well controlled right now. However, lower back pain can still be a real and ongoing issue even when M-protein levels are undetectable.

Here's why lower back pain can persist:

- Previous bone damage — Myeloma can cause bone lesions or structural changes in the spine that remain painful even after the disease is under control
- Light chains in the bone marrow — Even at 6–7%, abnormal plasma cells producing light chains can still affect bone marrow in localized areas
- Residual inflammation or nerve involvement — Past damage to the spine or surrounding tissue can cause ongoing discomfort It's absolutely worth raising this persistent lower back pain with the care team, even with good lab results. They may want to consider imaging like an MRI or CT scan to check for any bone changes or lesions that could explain the pain.

Pain management is a very valid part of myeloma care — good numbers don't mean discomfort should just be tolerated quietly!

May 28
A MyMyelomaTeam Member

Yes even chemo meds all cause back pain!

June 1

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