MyMyelomaTeam

What factors should you look for to determine your risk level with smoldering multiple myeloma (SMM)?

When reviewing your lab results, several key factors help determine your risk of progressing from SMM to active myeloma. Your healthcare team will evaluate these markers to categorize your risk level:

Key Risk Factors to Show Full Answer

What factors should you look for to determine your risk level with smoldering multiple myeloma (SMM)?

When reviewing your lab results, several key factors help determine your risk of progressing from SMM to active myeloma. Your healthcare team will evaluate these markers to categorize your risk level:

Key Risk Factors to Monitor:
* M protein levels higher than 15 grams per liter
* M protein type (IgA, IgM, or IgD carries higher risk than IgG)
* Abnormal free light chain ratio in your blood

Risk Level Categories:
* Low-risk: No risk factors present
* Low-intermediate risk: One risk factor
* High-intermediate risk: Two risk factors
* High-risk: Three risk factors

Additional factors your doctor may consider include the number of plasma cells in your bone marrow, whether M protein levels are increasing over time, any gene changes in plasma cells, and whether bone lesions appear on imaging tests.

Your doctor will review these lab results with you and explain what they mean for your individual situation. If you notice your M protein levels changing or have questions about any test results, don't hesitate to discuss them during your appointment.

 AI-generated responses are not a substitute for medical advice. These services are not intended to diagnose, treat, or cure any condition or disease. Always ask your doctor about specific health concerns.

Smoldering Multiple Myeloma: Your Guide

MGUS vs. Multiple Myeloma: What’s the Difference? (VIDEO)