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I asked because I added up the kappa and lambda values and it was the same as the paraprotein value. There are laboratories that do not measure M protein. According to the answer, separate M protein values should also be looked at.
No, M protein is not simply the sum of kappa and lambda paraproteins. M protein, also known as myeloma protein, monoclonal protein, M spike, or paraprotein, is produced by abnormal plasma cells. These proteins are monoclonal immunoglobulins, meaning they are identical antibodies produced by cloned abnormal plasma cells.
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