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MGUS is a precursor to MM. Usually the cancerous plasma cells are less than 10% of your bone marrow cells and there are no bone lesions nor kidney problems. MGUS patients are usually followed every six months to a year and no treatment is started unless high risk genetics are found. There is approximately a 1-2% increase yearly of getting full blown MM.
Monoclonal gammopathy of undetermined significance (MGUS) is classified as a benign condition within the spectrum of plasma cell disorders. It is at the mild end of this spectrum, with multiple myeloma being at the malignant end. MGUS requires observation rather than treatment, as it is asymptomatic and does not cause Show Full Answer
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