Are you wondering whether what you have is MGUS (Monoclonal Gammopathy of Undetermined Significance)?
MGUS is a non-cancerous condition where abnormal plasma cells produce a protein called M protein in the blood. It's considered a precursor to myeloma, but the risk of it progressing is quite low — about 1% per year.
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Are you wondering whether what you have is MGUS (Monoclonal Gammopathy of Undetermined Significance)?
MGUS is a non-cancerous condition where abnormal plasma cells produce a protein called M protein in the blood. It's considered a precursor to myeloma, but the risk of it progressing is quite low — about 1% per year.
Here are some key things to know about MGUS:
- It usually causes no symptoms
- It's often discovered accidentally during routine blood tests
- It's more common than myeloma, affecting 2–3% of people over 50
- Doctors typically recommend watchful waiting with regular blood and urine tests every 6–12 months
- It's classified as low, intermediate, or high risk for progression
The important distinction is that MGUS itself is not myeloma. Only a small number of people with MGUS will go on to develop active myeloma.
A confirmed diagnosis can only come from your doctor, based on blood tests measuring the type and amount of M protein present. If you're unsure about your diagnosis or results, it's always worth having a direct conversation with your care team.
October 23
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