For myeloma in general, research shows that people who had an early stem cell transplant stayed in remission for about 5.5 years (roughly 66 months) before relapse. However, high-risk myeloma tends to relapse sooner than standard-risk cases. For high-risk myeloma specifically, relapse can happen much earlier. Here are some Show Full Answer
For myeloma in general, research shows that people who had an early stem cell transplant stayed in remission for about 5.5 years (roughly 66 months) before relapse. However, high-risk myeloma tends to relapse sooner than standard-risk cases. For high-risk myeloma specifically, relapse can happen much earlier. Here are some key points to keep in mind:
- High-risk cytogenetic features (specific gene changes in myeloma cells) can make the disease more resistant to treatment
- Early relapse is generally defined as relapse within 12 months of treatment
- Those who relapse within one year tend to have a median overall survival of around 21 months
- The sooner a relapse happens after treatment, the more challenging the outlook becomes
It's really important to discuss your specific cytogenetic profile with your oncologist, as this plays a big role in predicting how your myeloma may respond after transplant. Maintenance therapy after transplant is often recommended to help delay relapse for as long as possible.
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