Stem cell transplants are a well-established part of myeloma treatment for many people. The most common type used for myeloma is an autologous stem cell transplant, where your own stem cells are collected, stored, and returned to your body after high-dose chemotherapy.
There are two main types to know about:
- Autologous – Show Full Answer
Stem cell transplants are a well-established part of myeloma treatment for many people. The most common type used for myeloma is an autologous stem cell transplant, where your own stem cells are collected, stored, and returned to your body after high-dose chemotherapy.
There are two main types to know about:
- Autologous – Uses your own stem cells. Lower risk of serious complications and is the standard recommended approach for myeloma
- Allogeneic – Uses a donor's stem cells. Less common, carries higher risks, and is mainly used in clinical trials or specific situations A transplant won't cure myeloma, but it can help extend remission. One large study found people who had an early transplant stayed in remission for around five and a half years before myeloma returned. Side effects are real and worth knowing about. Short-term ones can include:
- Nausea, vomiting, or diarrhea
- Fatigue and weakness
- Fever or infection
- Mouth and throat pain
Longer-term effects can include hormonal changes, cataracts, or organ changes. Your care team will monitor you closely throughout. A MyMyelomaTeam member who went through a transplant shared that asking for anti-nausea and anti-diarrhea medication early made a big difference — definitely don't try to tough it out! They also recommended bringing music, movies, and books, since rest is a big part of recovery.
Recovery typically means a 2–3 week hospital stay, though some people have outpatient transplants with daily monitoring. Your doctor will weigh your age, overall health, and other factors before recommending this path.
October 16
Join
Your Privacy Choices
