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Real members of MyMyelomaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
October 14
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MyMyelomaTeam

That's a frustrating situation, especially when you're trying to stay on top of your health on multiple fronts. The likely reason your colonoscopy was canceled relates to how Darzalex affects your blood and immune system.

Here are the key reasons a procedure might be postponed during Darzalex treatment:

- Low platelet counts Show Full Answer

That's a frustrating situation, especially when you're trying to stay on top of your health on multiple fronts. The likely reason your colonoscopy was canceled relates to how Darzalex affects your blood and immune system.

Here are the key reasons a procedure might be postponed during Darzalex treatment:

- Low platelet counts — Darzalex can reduce platelets, which are needed for blood clotting. Any procedure involving potential bleeding (like a colonoscopy with polyp removal) becomes riskier when platelets are low.
- Low white blood cell counts — Darzalex can suppress your immune system, making infection after a procedure a bigger concern.
- Blood matching interference — Darzalex affects certain blood tests, which can complicate pre-procedure preparations. The good news is this is likely a timing issue, not a permanent cancellation. Your care team will probably reschedule once your blood counts are in a safer range.

It's really worth having a direct conversation with both your oncologist and gastroenterologist so they can coordinate the best and safest timing together.

October 14

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