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Real members of MyMyelomaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
August 27
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A MyMyelomaTeam Member

Oh, and had two big side effects from Talvey: hands and feet peeling like crazy and NO sense of taste! Mouth so dry I can’t tolerate regular food—just soup and ice cream, jello, etc. Yuck

August 28
A MyMyelomaTeam Member

I had no side effects with Revlimid ( and the three accompanying chemo meds). On the other hand, they did very little for addressing my aggressive myeloma. When I switched to Talvey (immunotherapy) I got an immediate response and they are using that as a bridge to CAR-T cell therapy in October. Diagnosed May 2026

August 28
MyMyelomaTeam

First, a warm welcome — it's completely natural to have lots of questions right now, and asking them is a great first step in supporting your husband.

Lenalidomide (Revlimid) is one of the most commonly used treatments for myeloma, and while it's generally well tolerated, at least 20% of people do experience one or more Show Full Answer

First, a warm welcome — it's completely natural to have lots of questions right now, and asking them is a great first step in supporting your husband.

Lenalidomide (Revlimid) is one of the most commonly used treatments for myeloma, and while it's generally well tolerated, at least 20% of people do experience one or more side effects.

Here are the most commonly reported ones:

- Diarrhea or constipation
- Fatigue
- Swelling in the arms or legs
- Insomnia (difficulty sleeping)
- Muscle cramps or spasms
- Abdominal or back pain
- Nausea
- Fever
- Respiratory or digestive tract infections
- Cough
- Rash
- Shortness of breath
- Dizziness
- Loss of appetite
- Tremors

There are also some important things to be aware of. Lenalidomide can affect blood counts and may increase the risk of blood clots. It's also worth knowing there is a small but real risk of a secondary cancer developing, though the overall chance remains low.

The good news is that his medical team will monitor him closely during treatment. Any side effects that feel uncomfortable or concerning should always be reported to his doctor promptly — they can often help manage them effectively.

August 27

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