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Real members of MyMyelomaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Hi…I have MGUS for over 12 years and have an incredible Oncologist. I’ve been having full bloodwork tests and the 24 hour Urine Protein done

A MyMyelomaTeam Subscriber asked a question 💭

My Serum Free Light Chains numbers are stable but, are…ex
————
Kappa Free, Serum
View trends
Normal range: 0.33 - 1.94 mg/dL
(Phone number can only be seen by MyMyelomaTeam users).34
High
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Lambda Free, Serum
View trends
Normal range: 0.57 - 2.63 mg/dL
(Phone number can only be seen by MyMyelomaTeam users).78
———————
K/L FLC Ratio
View trends
Normal range: (Phone number can only be seen by MyMyelomaTeam users)
—————-
QUESTION
-> I am now taking: RAPATHA injections once every two… read more

August 7
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Can Certain Medications Raise the Risk for Developing Myeloma? Read Article...
MyMyelomaTeam

What a great question — and 12 years of stable MGUS with a great oncologist is genuinely something to feel good about! 🙌

Regarding Repatha (evolocumab) and any link to myeloma, there is currently no established evidence in available research suggesting that Repatha causes or accelerates myeloma or MGUS progression. It Show Full Answer

What a great question — and 12 years of stable MGUS with a great oncologist is genuinely something to feel good about! 🙌

Regarding Repatha (evolocumab) and any link to myeloma, there is currently no established evidence in available research suggesting that Repatha causes or accelerates myeloma or MGUS progression. It works very differently from statins, as it's a PCSK9 inhibitor that targets a specific protein to lower LDL. Regarding Crestor (rosuvastatin) and myeloma, there has been some early research interest in whether statins might have a protective effect. However, this research is still very preliminary and not yet conclusive enough to make firm recommendations.

It's worth noting that your Kappa Free Light Chain being slightly elevated while your Lambda and K/L ratio remain within range is something your oncologist is clearly already monitoring closely — which is exactly the right approach. Here are the key takeaways worth discussing with your oncologist:

- Repatha — no current evidence linking it to myeloma development
- Crestor — some early interest in a possible protective role, but not proven
- Your slightly elevated Kappa FLC — stable trends matter most, and your team is watching it well
- Any medication changes — always worth running past your oncologist given your MGUS history

Your oncologist is really your best guide here, especially when weighing medication choices alongside your MGUS monitoring.

August 7

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