Induction therapy for myeloma typically involves a combination of drugs — often including a proteasome inhibitor, an immunomodulatory drug, and a steroid (sometimes with a monoclonal antibody added). Each drug type brings its own set of potential side effects.
Here are the most commonly reported ones:
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Induction therapy for myeloma typically involves a combination of drugs — often including a proteasome inhibitor, an immunomodulatory drug, and a steroid (sometimes with a monoclonal antibody added). Each drug type brings its own set of potential side effects.
Here are the most commonly reported ones:
From chemotherapy/general treatment:
- Tiredness and fatigue
- Nausea, vomiting, or diarrhea
- Hair loss
- Mouth sores
- Low blood cell counts (raising infection and bleeding risk)
From steroids (like dexamethasone):
- Sleep problems
- Mood changes
- High blood sugar
- Bone weakening
From immunomodulatory drugs (like lenalidomide):
- Blood clots
- Nerve damage (tingling or numbness)
- Anemia and infections
From targeted therapies:
- Rashes
- Swelling
- Breathing problems
- Fatigue
It's worth noting that not everyone experiences every side effect — and your care team can help manage most of them. Always flag any new or worsening symptoms to your doctor promptly, as some side effects can become serious if left unaddressed.
August 7