MyMyelomaTeam

Swelling in the leg and foot can happen for several myeloma-related reasons. It's really important to mention this to your doctor, especially if it's sudden or getting worse.

Here are some possible myeloma-related causes:

- Nerve damage (peripheral neuropathy) — myeloma can damage nerves, which may affect circulation and Show Full Answer

Swelling in the leg and foot can happen for several myeloma-related reasons. It's really important to mention this to your doctor, especially if it's sudden or getting worse.

Here are some possible myeloma-related causes:

- Nerve damage (peripheral neuropathy) — myeloma can damage nerves, which may affect circulation and cause swelling
- Kidney involvement — myeloma can affect kidney function, which can lead to fluid buildup in the legs and feet
- Hypercalcemia — a buildup of calcium in the blood caused by myeloma can contribute to muscle and tissue issues
- Treatment side effects — some myeloma medications can affect muscle tissue and circulation

A few things to watch for that need *immediate* medical attention:

- Sudden, severe leg pain alongside back pain
- Numbness or muscle weakness in the leg
- Loss of bladder or bowel control

These could signal spinal cord compression, which is a medical emergency. In the meantime, keeping the leg elevated when resting may help reduce swelling. But please don't wait too long to bring this up with your care team — they can run blood tests to find the exact cause and recommend the right treatment for you.

 AI-generated responses are not a substitute for medical advice. These services are not intended to diagnose, treat, or cure any condition or disease. Always ask your doctor about specific health concerns.

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