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I just saw my Rheumatologist yesterday and he has ordered a new MRI, my Oncologist saw me in hall and asked why I was visiting the doctor and I Said "my foot is swollen like it is fractured again, and her statement was " I am going to have to change your medicine. I ask AI and this was answer: Lenalidomide is known to cause fluid and retention and swelling in arms, hands, legs or feet. Swelling in one leg or foot accompanied by bone marrow edema is serious it could cause a blood clot. I take… read more

May 21
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MyMyelomaTeam

What a lot to deal with so soon after starting a new medication — that's genuinely tough, and it's great that both your Rheumatologist and Oncologist are already on it.

Swelling in the limbs is a recognized side effect of lenalidomide. When swelling appears in just one foot or leg, it does warrant closer attention, as it Show Full Answer

What a lot to deal with so soon after starting a new medication — that's genuinely tough, and it's great that both your Rheumatologist and Oncologist are already on it.

Swelling in the limbs is a recognized side effect of lenalidomide. When swelling appears in just one foot or leg, it does warrant closer attention, as it can sometimes be associated with a blood clot (deep vein thrombosis). The good news is that you're already doing the right things:

- Blood thinners — you're already on these, which is the standard precaution for people on lenalidomide
- MRI ordered — this will help clarify what's happening in your foot
- Oncologist aware — and already considering a medication change

Since your oncologist is already talking about switching medications, that conversation is really important to have fully. There are alternative treatment options available if lenalidomide isn't working well for you.

Keep monitoring symptoms closely. If swelling worsens, or you develop chest pain or shortness of breath, seek emergency care immediately — don't wait for a scheduled appointment.

May 21
A MyMyelomaTeam Member

I am having trouble with swelling in both legs, but it is from Ninlaro as I am not on Lenalidomide. I was only on it for 4 months as it affected my hearing.

May 21
A MyMyelomaTeam Member

I’m sorry you are having this problem.💕

May 21

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