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Real members of MyMyelomaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyMyelomaTeam Member asked a question 💭
West Des Moines, IA
June 16
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A MyMyelomaTeam Member

Yes I have used it since a relapse in 2019 through 2024. Part of the time was for maintenance and my choice. I have had infusion and later the shots. Of course the shots take way less time. I tolerated both well. Tiredness seemed one of the only side effects. I had them once a month at the time. It has been 2 yrs since and meds and am now getting blood work every 3 months. We are expanding the time between blood testing.

June 16
MyMyelomaTeam

It sounds like you're asking about daratumumab (Darzalex) for smoldering myeloma — great question! While Darzalex is FDA-approved for active myeloma, its use for smoldering myeloma is still being explored in clinical trials rather than as a standard treatment.

A clinical trial launched in 2017 has been studying daratumumab Show Full Answer

It sounds like you're asking about daratumumab (Darzalex) for smoldering myeloma — great question! While Darzalex is FDA-approved for active myeloma, its use for smoldering myeloma is still being explored in clinical trials rather than as a standard treatment.

A clinical trial launched in 2017 has been studying daratumumab in adults with smoldering myeloma, monitoring safety, side effects, and whether it can slow or prevent progression to active myeloma. As for personal experiences from the community, a MyMyelomaTeam member may have shared insights on this, but it's still a relatively emerging area.

It's worth having a conversation with your oncologist about whether a clinical trial involving daratumumab might be a good fit. You can also explore options at ClinicalTrials.gov to find studies you may qualify for.

Keep in mind that for smoldering myeloma, some doctors take a "watchful waiting" approach, while others may recommend bone-strengthening medications like bisphosphonates to protect against bone damage in the meantime.

June 16

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