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June 11
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Multiple Myeloma – The Path to Diagnosis Read Article...
MyMyelomaTeam

It sounds frustrating to feel like your concerns aren't being fully heard, especially when your M-spike is elevated. That's completely understandable.

With MGUS, a high M-spike is one of the key risk factors doctors watch closely. The risk factors that can indicate a higher chance of progression include:

- M protein Show Full Answer

It sounds frustrating to feel like your concerns aren't being fully heard, especially when your M-spike is elevated. That's completely understandable.

With MGUS, a high M-spike is one of the key risk factors doctors watch closely. The risk factors that can indicate a higher chance of progression include:

- M protein levels higher than 15 grams per liter
- M protein type IgA, IgM, or IgD (rather than IgG)
- An abnormal free light chain ratio in your blood

The more of these factors present, the higher the risk level — ranging from low-risk to high-risk. Regarding the recurring UTIs, a weakened immune system is associated with MGUS and myeloma, which can make infections more likely. It's worth raising this connection directly with your doctor and asking whether your M-spike level warrants more frequent monitoring or a referral to a hematologist (a blood specialist) if you don't already see one.

Don't be afraid to advocate for yourself — asking your doctor to explain your specific risk level based on your current numbers is a very reasonable request.

June 11

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