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Real members of MyMyelomaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyMyelomaTeam Member asked a question 💭
Roodepoort, ZA
May 27
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Lenalidomide (Revlimid) is a commonly used myeloma treatment, and while it's generally well tolerated, at least 1 in 5 people experience one or more side effects. Here's a summary of what to watch for:

Common side effects
- Diarrhea or constipation
- Fatigue
- Nausea
- Muscle cramps or spasms
- Swelling in the arms or Show Full Answer

Lenalidomide (Revlimid) is a commonly used myeloma treatment, and while it's generally well tolerated, at least 1 in 5 people experience one or more side effects. Here's a summary of what to watch for:

Common side effects:
- Diarrhea or constipation
- Fatigue
- Nausea
- Muscle cramps or spasms
- Swelling in the arms or legs
- Insomnia
- Rash
- Loss of appetite
- Dizziness or tremors
- Cough or shortness of breath

More serious risks to be aware of:
- Changes in blood counts (low red or white blood cells, or platelets)
- Higher risk of blood clots — aspirin or a blood thinner may help reduce this risk
- Increased risk of infections
- Nerve damage
- A small but real increased risk of a secondary cancer (estimated between 1.5% and 7.4%)

It's really important to report any side effects to your healthcare team as soon as they appear. Many side effects can be managed effectively, and your doctor may adjust your dose or recommend supportive treatments to help keep you comfortable.

May 27

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