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One would think that one’s body would get used to this reaction since my first was 1/22/26. Anyone in the MajesTEC 7 clinical trial having this issue. Doc prescribed Triamcinolone Acetonide Cream! Just curious

April 16
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MyMyelomaTeam

Are you experiencing itching and rash around the infusion site after your Darzalex Faspro and talquetamab treatment?

Rash and injection site reactions are known side effects of both medications you're receiving. Talquetamab specifically can cause rash as a side effect, and injection site pain is also commonly reported with Show Full Answer

Are you experiencing itching and rash around the infusion site after your Darzalex Faspro and talquetamab treatment?

Rash and injection site reactions are known side effects of both medications you're receiving. Talquetamab specifically can cause rash as a side effect, and injection site pain is also commonly reported with these treatments.

It's actually not unusual for these reactions to continue occurring even after multiple cycles. Your body doesn't necessarily build tolerance to these side effects over time, as they're related to how the medications interact with your immune system and skin.

The triamcinolone cream your doctor prescribed is a topical steroid that should help with the itching. Here are some tips that may also help:

* Apply the cream as directed by your doctor
* Keep the area moisturized (use fragrance-free products)
* Avoid scratching, which can worsen irritation
* Consider applying moisturizer right after bathing to seal it in

A MyMyelomaTeam member shared a similar experience, noting they tried changing injection sites to reduce side effects. You might ask your care team if alternating sites could help, though always follow their guidance.

Keep your oncology team informed about how the rash responds to treatment, especially if it worsens or spreads beyond the injection site.

April 16

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