What would you like to know about Blenrep?
Blenrep (belantamab mafodotin-blmf) is an antibody-drug conjugate used to treat relapsed or refractory multiple myeloma. It works by targeting a protein called BCMA that's found on myeloma cells.
Here's how it works:
* The antibody part attaches to BCMA on myeloma cells
* It Show Full Answer
What would you like to know about Blenrep?
Blenrep (belantamab mafodotin-blmf) is an antibody-drug conjugate used to treat relapsed or refractory multiple myeloma. It works by targeting a protein called BCMA that's found on myeloma cells.
Here's how it works:
* The antibody part attaches to BCMA on myeloma cells
* It delivers a cancer-killing drug directly into those cells
* It also helps your immune system's natural killer cells destroy myeloma cells
When it's used:
Blenrep is approved in combination with bortezomib and dexamethasone for adults who have tried at least two prior treatments, including a proteasome inhibitor and an immunomodulatory drug.
Important to know:
Eye-related side effects are a concern with Blenrep, so regular eye exams are necessary during treatment. The medication was temporarily pulled from the U.S. market in 2022 but was reapproved by the FDA in October 2025.
Is there something specific about Blenrep you'd like to understand better?
April 8