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A MyMyelomaTeam Member asked a question 💭
Loretto, PA

My husband will be starting a new treatment soon his light chain myeloma numbers are rising. He will be on Elotuzumab and pomalyst and dexamethasone. Anyone have information a this ? Side effects?

March 30
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A MyMyelomaTeam Member

I've been on a monoclonal antibody Darzalex, with Pomalyst for a long time. I hope he does great with this treatment 🙏

March 30
MyMyelomaTeam

What can you tell me about the side effects of elotuzumab, pomalidomide (Pomalyst), and dexamethasone treatment?

Your husband's treatment combination is designed to target myeloma cells in multiple ways. Elotuzumab is a monoclonal antibody that helps the immune system recognize and attack myeloma cells, while pomalidomide Show Full Answer

What can you tell me about the side effects of elotuzumab, pomalidomide (Pomalyst), and dexamethasone treatment?

Your husband's treatment combination is designed to target myeloma cells in multiple ways. Elotuzumab is a monoclonal antibody that helps the immune system recognize and attack myeloma cells, while pomalidomide boosts immune response and dexamethasone is a corticosteroid that works alongside these drugs.

Here are the potential side effects to be aware of:

Elotuzumab side effects:
* Temporary fever, chills, dizziness, or trouble breathing soon after infusion
* Loss of appetite
* Diarrhea
* Fever
* Peripheral neuropathy (nerve damage causing numbness or tingling)
* Upper respiratory tract infections

Pomalidomide side effects:
* Fatigue or drowsiness
* Constipation
* Low blood cell counts
* Neuropathy
* Blood clots
* Nausea and vomiting

Dexamethasone side effects:
* Increased appetite and weight gain
* Mood changes
* Trouble sleeping
* Weakened bones with long-term use
* Immune system suppression

It's important to stay in close contact with your husband's healthcare team about any side effects. They can often help manage symptoms and adjust treatment if needed. Many side effects are temporary and improve after treatment ends.

March 30

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