Smoldering has to be very anxiety provoking. MSK is doing clinical trials for Smoldering related to a plant based diet. There are also clinical trials for high risk Smoldering.
March 3
What treatment options are available for smoldering myeloma?
For smoldering myeloma (SMM), the most common approach is watchful waiting, also called observation. This means your doctor will monitor your condition with regular tests and examinations without starting treatment right away. This helps you avoid treatment side Show Full Answer
What treatment options are available for smoldering myeloma?
For smoldering myeloma (SMM), the most common approach is watchful waiting, also called observation. This means your doctor will monitor your condition with regular tests and examinations without starting treatment right away. This helps you avoid treatment side effects while keeping a close eye on any changes.
However, treatment approaches are evolving. If you have high-risk smoldering myeloma—meaning your myeloma cells have specific genetic characteristics that suggest a higher chance of progression—your doctor might recommend starting treatment earlier than usual.
Some treatment options that may be considered include:
* Bisphosphonates - Drugs like Aredia (pamidronate), Xgeva (denosumab), and Zometa (zoledronic acid) that strengthen bones and protect against bone damage
* Lenalidomide (Revlimid) with low-dose dexamethasone (Decadron) - Clinical trials have shown this combination may reduce the chances of developing active myeloma in people with higher-risk SMM
Recent evidence suggests that earlier treatment may improve outcomes for people with high-risk smoldering myeloma. Your healthcare team will assess your individual risk factors to determine the best approach for you.
March 3
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