What is light chain lambda smoldering myeloma with translocation (11:14)?
You have a specific type of myeloma that involves lambda light chains. In light chain myeloma, the cancerous plasma cells produce only the light chain portion of antibodies (also called Bence Jones proteins), rather than complete antibodies.
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What is light chain lambda smoldering myeloma with translocation (11:14)?
You have a specific type of myeloma that involves lambda light chains. In light chain myeloma, the cancerous plasma cells produce only the light chain portion of antibodies (also called Bence Jones proteins), rather than complete antibodies.
Smoldering myeloma means you have abnormal plasma cells and proteins in your body, but you may not have symptoms yet. Some people with smoldering myeloma don't require treatment right away - they're monitored closely instead.
The (11:14) refers to a chromosomal translocation, which is a genetic change in the myeloma cells. This is important information that helps your doctor understand your specific type of myeloma and plan the best approach for monitoring or treatment.
Light chain myeloma carries a higher risk of kidney damage compared to other types. The light chains are small enough to circulate easily in your bloodstream and can clog the tiny filters in your kidneys, potentially causing inflammation and damage over time.
Watch for symptoms like:
- Changes in urination
- Swollen feet and ankles
- Fatigue or weakness
- Bone pain
Your doctor will likely monitor your kidney function closely through blood and urine tests. If you develop symptoms or your condition progresses, treatment options are similar to other forms of myeloma and may include proteasome inhibitors, immunomodulators, and steroids.
March 2
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