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My blood test results are:
IgA - 1450 mg/dl, IgG - 1613 mg/dl, IgM - 49 mg/dl.
But, my oncologist uses Abnormal protein band 1 & 2. They show 1.2 and 0.9 g/dl, respectively.
How do these results match up with your information/answer to the above question?

February 19
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MyMyelomaTeam

What are the blood test numerical readings for M protein for different stages of myeloma for IgA, IgM, or IgG, and how do your results compare?

The Durie-Salmon Staging System uses M protein levels to help classify myeloma stages:

Stage 1 criteria include
- IgG M protein less than 50 grams per liter (5,000 mg/dL)
- IgA M Show Full Answer

What are the blood test numerical readings for M protein for different stages of myeloma for IgA, IgM, or IgG, and how do your results compare?

The Durie-Salmon Staging System uses M protein levels to help classify myeloma stages:

Stage 1 criteria include:
- IgG M protein less than 50 grams per liter (5,000 mg/dL)
- IgA M protein less than 30 grams per liter (3,000 mg/dL)

Stage 3 criteria include:
- IgG M protein greater than 70 grams per liter (7,000 mg/dL)
- IgA M protein greater than 50 grams per liter (5,000 mg/dL)

Your results show total immunoglobulin levels (IgA 1,450 mg/dL, IgG 1,613 mg/dL), which include both normal and abnormal antibodies. The abnormal protein bands your oncologist tracks (1.2 and 0.9 g/dL, or 1,200 and 900 mg/dL) represent the actual M protein levels.

These band measurements are more specific for tracking myeloma activity. Converting to grams per liter, your M protein levels would be 12 g/L and 9 g/L, which fall below the Stage 1 thresholds mentioned above.

Your oncologist is using the right approach by tracking those specific abnormal protein bands rather than total immunoglobulin levels, as they give a clearer picture of disease activity.

February 19

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