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Real members of MyMyelomaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
January 28
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A MyMyelomaTeam Member

It’s a good chemo drug I never had side effects and it kills cancer cells

February 2
A MyMyelomaTeam Member

Thank you for your response. I'll further discuss my options with my Oncologist.

February 2
A MyMyelomaTeam Member

Darzalex is highly recommended.
I never had problems with it.

February 2
MyMyelomaTeam

Has anyone used Darzalex, and what should you know about it being added to your treatment?

Yes, many MyMyelomaTeam members have experience with Darzalex. It's actually not the newest drug anymore—it's been widely used and has become a standard part of many myeloma treatment regimens.

Darzalex (daratumumab) is a monoclonal Show Full Answer

Has anyone used Darzalex, and what should you know about it being added to your treatment?

Yes, many MyMyelomaTeam members have experience with Darzalex. It's actually not the newest drug anymore—it's been widely used and has become a standard part of many myeloma treatment regimens.

Darzalex (daratumumab) is a monoclonal antibody that targets a protein called CD38 found on myeloma cells. It works by helping your immune system recognize and destroy these cancer cells.

How it's used:
- Often combined with other drugs like lenalidomide (Revlimid), bortezomib (Velcade), and dexamethasone
- Can be used for newly diagnosed myeloma or when myeloma returns
- Sometimes used as maintenance therapy after bone marrow transplant

Two forms available:
- IV infusion (Darzalex)
- Subcutaneous injection under the skin (Darzalex Faspro)—this version is much faster to administer

Common side effects to be aware of:
- Nausea
- Back pain
- Fever
- Cough
- Fatigue
- Low blood cell counts
- Rarely, breathing problems or dizziness during infusion

Darzalex has been a breakthrough in myeloma treatment and has helped many people achieve better outcomes. It's worth discussing with your doctor why they're recommending it for your specific situation and which form might work best for you.

January 28

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