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A MyMyelomaTeam Member asked a question 💭
Scottsdale, AR

I’m in my second month and last week and now I have a fever. It is low grade with no other symptoms except I feel terrible.

December 10, 2025
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A MyMyelomaTeam Member

Have not experienced this, except for the first two treatments.

December 11, 2025
A MyMyelomaTeam Member

I dont get a fever per say but I do feel a bit warmer than the outside temps would justify, especially my feet, but by the next day it is usually gone, except my feet still get waves of warmth.

December 10, 2025
MyMyelomaTeam

Can fever occur as a delayed reaction after Darzalex Faspro injection?

Fever is a recognized side effect of Darzalex Faspro (daratumumab and hyaluronidase-fihj). While the medication can cause immediate reactions like fever, chills, dizziness, or breathing trouble soon after receiving the injection, fever can also occur as Show Full Answer

Can fever occur as a delayed reaction after Darzalex Faspro injection?

Fever is a recognized side effect of Darzalex Faspro (daratumumab and hyaluronidase-fihj). While the medication can cause immediate reactions like fever, chills, dizziness, or breathing trouble soon after receiving the injection, fever can also occur as one of the more common side effects during treatment.

If you're experiencing a fever after your Darzalex Faspro injection, it's important to contact your healthcare team. They can help determine whether this is a typical side effect or if it might indicate something that needs additional attention, such as an infection.

Other common side effects you might experience with Darzalex Faspro include:
* Nausea
* Back pain
* Cough
* Fatigue
* Low blood cell counts

Keep track of when the fever started, how high it is, and any other symptoms you're experiencing. This information will help your doctor assess your situation and provide appropriate guidance.

December 10, 2025

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