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I ended my multiple RVD myeloma treatment on 9-27-25 with a m-protein level of .30. Will the neuropathy ever go away?

A MyMyelomaTeam Member asked a question 💭
Charlotte, MI
November 11, 2025
 · 
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A MyMyelomaTeam Member

Hi Rod,
In March my M protein was 0.6. Now it is 0.5. I’m working on changing my diet and supplements to see if I can bring it down. FYI, ,y mom took 2 heaping teaspoons of Nutritional Yeast multiple times a day. I only do it once in the morning. Even with all the strong chemo she got with ovarian cancer, she never got neuropathy.
Paula🌹

November 18, 2025
A MyMyelomaTeam Member

Thanks Paula! I'll give Bob's Red Mill Nutritional Yeast a try. Also, with smoldering myeloma, what is your m-protein level. I have a friend with SMG and at this point, he has no symptoms. Thanks again, Rod

November 18, 2025
A MyMyelomaTeam Member

Hi Rod,
I don’t know if this will help, but I am Smoldering and have had neuropathy since 2014. After I started taking 2 heaping teaspoons of Bob’s RedMill Nutritional Yeast, it has gotten better. My mother took it when she had chemo for ovarian cancer and she never got neuropathy.
Paula🌹

November 11, 2025
MyMyelomaTeam

Will the neuropathy from your RVD treatment go away?

The answer varies from person to person. Some good news: neuropathy can improve or even disappear once treatment ends or the dose is lowered. A MyMyelomaTeam member shared they had numbness and severe bone pain requiring a walker during treatment, but walked without Show Full Answer

Will the neuropathy from your RVD treatment go away?

The answer varies from person to person. Some good news: neuropathy can improve or even disappear once treatment ends or the dose is lowered. A MyMyelomaTeam member shared they had numbness and severe bone pain requiring a walker during treatment, but walked without assistance for 10 years afterward.

However, for others, nerve damage persists. Some members experience pain and tingling long after treatment is over. As one member learned from their neurologist, both myeloma itself and chemotherapy can cause neuropathy, making it challenging to predict.

The timeline matters too. Some people see improvement within months, while others may not. If neuropathy hasn't improved after about four years, it may be permanent for some individuals.

Since you just finished treatment in late September, it's still early. Your body needs time to recover. Contact your doctor immediately if symptoms worsen, and discuss treatment options like prescription medications (antidepressants, anticonvulsants, or pain medications) if the neuropathy becomes difficult to manage.

Your M-protein level of 0.30 suggests good response to treatment, which is encouraging for your overall outlook.

November 11, 2025

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