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A MyMyelomaTeam Member asked a question 💭
Roodepoort, ZA
October 24, 2025
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MyMyelomaTeam

How can fatigue related to myeloma be managed?

Fatigue is one of the most common and challenging symptoms for people living with myeloma. Unlike regular tiredness, cancer-related fatigue doesn't go away with rest and can feel overwhelming.

There are several main causes of fatigue in myeloma:

* Anemia - When myeloma cells Show Full Answer

How can fatigue related to myeloma be managed?

Fatigue is one of the most common and challenging symptoms for people living with myeloma. Unlike regular tiredness, cancer-related fatigue doesn't go away with rest and can feel overwhelming.

There are several main causes of fatigue in myeloma:

* Anemia - When myeloma cells interfere with bone marrow function, reducing red blood cells that carry oxygen throughout your body
* High cytokine levels - These immune system proteins can cause persistent inflammation
* Pain from the condition itself
* Emotional stress, anxiety, and depression
* Treatment side effects from medications
* Poor sleep, nutrition, or reduced physical activity

Managing fatigue takes a methodical approach. Here are some strategies that can help:

Start an exercise routine - Even light activity like walking around the yard can make a difference. Gradually increase as you build strength.

Focus on nutrition - Work with a dietitian to ensure you're getting enough calories and nutrients to support your energy needs.

Improve sleep habits - Pay attention to your sleep quality, as medications like steroids can interfere with rest.

Address reversible causes - Your care team can check for treatable factors like anemia, pain, or anxiety.

Practice self-compassion - Many MyMyelomaTeam members remind each other not to overdo it and listen to what their body is telling them.

As your myeloma treatment progresses and becomes more effective, fatigue often improves. Stay patient with yourself and keep your healthcare team informed about how fatigue is affecting your daily life.

October 24, 2025

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