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September 3, 2025
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What causes itching with multiple myeloma?

Itchy skin can occur due to several myeloma-related factors
• The myeloma itself (affects about 1% of patients)
• Complications like chronic kidney disease
• Treatment side effects from medications like lenalidomide
• Radiation therapy
• Bone marrow transplants Here are some ways Show Full Answer

What causes itching with multiple myeloma?

Itchy skin can occur due to several myeloma-related factors:
• The myeloma itself (affects about 1% of patients)
• Complications like chronic kidney disease
• Treatment side effects from medications like lenalidomide
• Radiation therapy
• Bone marrow transplants Here are some ways to manage itchy skin:

• Use over-the-counter anti-itch creams (check with your healthcare team first)
• Ask about prescription steroid creams for short-term use
• Stay well hydrated
• Apply fragrance-free moisturizer twice daily
• Talk to your healthcare team if itching is severe or disrupting sleep

Remember that while itching can be frustrating, there are multiple options to help manage this symptom. Your healthcare team can help identify the specific cause and recommend the most appropriate treatment approach.

September 3, 2025

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