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Real members of MyMyelomaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

I have already received denosumab 3 times (Prolia 60 mg every six months) for osteoporosis, but my DEXA score is still deteriorating, currently my T-score is -4.5. I should switch to teriparatide or romosozumab (Evenity). Does anyone have experience with these?

June 16, 2025
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MyMyelomaTeam

While denosumab is commonly used in myeloma treatment, it's important to be aware that it can increase the risk of developing osteonecrosis of the jaw. Before switching medications, it would be advisable to discuss this with both your oncologist and dentist.

If you're experiencing ongoing bone concerns, your healthcare Show Full Answer

While denosumab is commonly used in myeloma treatment, it's important to be aware that it can increase the risk of developing osteonecrosis of the jaw. Before switching medications, it would be advisable to discuss this with both your oncologist and dentist.

If you're experiencing ongoing bone concerns, your healthcare team may need to reevaluate your overall treatment plan, as bone health is a crucial aspect of myeloma management. It's important to note that treatment plans often need to be tailored to each individual's specific situation. Factors such as age, disease severity, and overall health status all play a role in determining the most effective treatment approach. Your oncologist will be best positioned to evaluate whether a change in medication is appropriate for your specific case.

June 16, 2025

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