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Real members of MyMyelomaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Is A Very Slow Serum Light Chain Ratio Reduction Cause For Concern?

A MyMyelomaTeam Member asked a question 💭
Johannesburg, Gauteng

I have had one hell of a journey till now. I have light chain myeloma and was stage 3 when diagnosed with over 90% plasma cell infiltration. I had induction therapy with VRD and a stem cell transplant in January. Bone marrow aspiration shows a reduction to 1-3% plasma cells. Everything else is gone except that I still had a kappa lambda ratio of 24. Just completed my first cycle of consolidation, and ration only reduced to 20. This concerns me, as literature says the sooner serum light chain… read more

May 4, 2023
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A MyMyelomaTeam Member

I try not to read too much literature on google. Because I know some people who had the worst prognosis who are still doing well many many years later. Averages can be very misleading too.

January 26, 2024
A MyMyelomaTeam Member

However…it was over 3000 when I was diagnosed, so there has been a significant reduction

May 4, 2023
A MyMyelomaTeam Member

I am living proof of that👍🥰

January 26, 2024
A MyMyelomaTeam Member

Hi Kate, hopefully your ratio will normalize. It took over a year after transplant for my m spike to go away💕

May 4, 2023
A MyMyelomaTeam Member

I’m a bit confused. When I checked lambda kappa ratio normal is .26-1.65. So is yours .24. I’m new to all this and trying to figure out my hubby’s scores

May 4, 2023

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What Specifically Constitutes Kappa Light Chain Myeloma?

A MyMyelomaTeam Member asked a question 💭
Snyder, TX

Immunoglobulin G, A, & M Ranges Are Normal. Immunofixation Serum Is Normal. KAPPA Light Chain 31.6 Lambda 17.1 & Kappa/Lambda Ratio1.85.

A MyMyelomaTeam Member asked a question 💭
Concord, NC

Can A Person Have An Abnormal Free Light Chain Ratio And Not Have The Light Chain Form Of Multiple Myeloma?

A MyMyelomaTeam Member asked a question 💭
New York, NY
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