Is A Very Slow Serum Light Chain Ratio Reduction Cause For Concern? | MyMyelomaTeam

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Is A Very Slow Serum Light Chain Ratio Reduction Cause For Concern?
A MyMyelomaTeam Member asked a question 💭

I have had one hell of a journey till now. I have light chain myeloma and was stage 3 when diagnosed with over 90% plasma cell infiltration. I had induction therapy with VRD and a stem cell transplant in January. Bone marrow aspiration shows a reduction to 1-3% plasma cells. Everything else is gone except that I still had a kappa lambda ratio of 24. Just completed my first cycle of consolidation, and ration only reduced to 20. This concerns me, as literature says the sooner serum light chain… read more

posted May 4, 2023
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A MyMyelomaTeam Member

I try not to read too much literature on google. Because I know some people who had the worst prognosis who are still doing well many many years later. Averages can be very misleading too.

posted January 26
A MyMyelomaTeam Member

However…it was over 3000 when I was diagnosed, so there has been a significant reduction

posted May 4, 2023
A MyMyelomaTeam Member

I am living proof of that👍🥰

posted January 26
A MyMyelomaTeam Member

Hi Kate, hopefully your ratio will normalize. It took over a year after transplant for my m spike to go away💕

posted May 4, 2023
A MyMyelomaTeam Member

I’m a bit confused. When I checked lambda kappa ratio normal is .26-1.65. So is yours .24. I’m new to all this and trying to figure out my hubby’s scores

posted May 4, 2023

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