Even myeloma experts do not agree on the answer to your question. There are many factors that have to be considered, so it is a personal choice about which considerations are most important to you as an individual. There is no one correct answer that fits everyone. So, whatever you decide is right for you. I had an autologous SCT back in 1999 when I was in my mid-50s and in otherwise good health. I had over 2 years of remission before I relapsed. Would I make the same decision at my current age and with my other health issues? No, but I am glad I did it in 1999.