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Having alot of painful pvcs today. Have been on propafenone for heart arrhythmia Doing darzalex injections for high risk smoldering myeloma.

A MyMyelomaTeam Member asked a question 💭
Laporte, IN
October 24
 · 
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A MyMyelomaTeam Member

Yes, got ahold of doctor on duty tonight. For now they stopped. He said to make sure that I'm getting enough fluids to stay hydrated, check blood pressure no caffeine. If comes back then go to ER. Possibly anxiety, he said I might talk to my Oncologist about a prescription for anxiety.

October 24
MyMyelomaTeam

That sounds really uncomfortable — painful PVCs are no fun at all. The important question here is: could Darzalex be playing a role in what you're experiencing today?

Darzalex (daratumumab) is not commonly known to directly cause heart arrhythmias, but it can cause side effects that may stress the body, including:

- Fatigue
- Show Full Answer

That sounds really uncomfortable — painful PVCs are no fun at all. The important question here is: could Darzalex be playing a role in what you're experiencing today?

Darzalex (daratumumab) is not commonly known to directly cause heart arrhythmias, but it can cause side effects that may stress the body, including:

- Fatigue
- Shortness of breath
- Fever
- Fluid retention (swelling)

These can sometimes make existing heart rhythm issues feel worse. Since you're already on propafenone to manage arrhythmia, it's really important to contact your care team today — not tomorrow — about the increase in painful PVCs. They need to know because:

- Your Darzalex schedule or dosing may need to be reviewed
- Your propafenone dose may need adjusting
- Some Darzalex side effects can interact with how your heart responds

Please don't wait this one out. Reach out to your oncologist or cardiologist as soon as possible today. They're the best people to figure out if these two treatments need to be better coordinated.

October 24
A MyMyelomaTeam Member

Contact your Hematologist. Let them know you may be having side effects.
Paula🌹

October 24

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