MyMyelomaTeam

It's really common to experience neuropathy with myeloma, and you're definitely not alone in this. Neuropathy in the legs and even the face can have a few different causes related to myeloma itself — not just the treatments.

Here are the main reasons neuropathy can develop:

- The disease itself — Myeloma can cause abnormal Show Full Answer

It's really common to experience neuropathy with myeloma, and you're definitely not alone in this. Neuropathy in the legs and even the face can have a few different causes related to myeloma itself — not just the treatments.

Here are the main reasons neuropathy can develop:

- The disease itself — Myeloma can cause abnormal proteins (M protein) to build up in the blood, which can directly damage nerves
- Treatments like Revlimid — Immunomodulatory drugs can cause or worsen nerve damage as a side effect
- Bone lesions — If myeloma has affected bones near nerves (like the jaw or spine), this can cause numbness or tingling in unexpected places like the face or legs A MyMyelomaTeam member shared that their oncologist confirmed bone lesions on the jaw and skull were causing facial numbness — so facial neuropathy, while less talked about, is a real experience for some people.

It's worth discussing with your oncology team, as they may be able to adjust treatment or help manage symptoms. Sometimes reducing a dose can make a difference.

 AI-generated responses are not a substitute for medical advice. These services are not intended to diagnose, treat, or cure any condition or disease. Always ask your doctor about specific health concerns.

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