It sounds like you're asking about smoldering myeloma (SMM) — an easy name to mix up! SMM is a precancerous condition that sits between a mild condition called MGUS and active multiple myeloma.
People with SMM have too many abnormal plasma cells and elevated levels of a protein called M protein in their blood, but don't yet Show Full Answer
It sounds like you're asking about smoldering myeloma (SMM) — an easy name to mix up! SMM is a precancerous condition that sits between a mild condition called MGUS and active multiple myeloma.
People with SMM have too many abnormal plasma cells and elevated levels of a protein called M protein in their blood, but don't yet have symptoms or organ damage. Because it causes no symptoms, SMM is often discovered accidentally during routine blood tests.
The risk of SMM progressing to active myeloma decreases over time:
- First 5 years: ~10% chance per year
- Years 5–10: ~3% chance per year
- After 10 years: ~1% chance per year Management options for SMM can include:
- Watchful waiting — regular monitoring with blood tests and check-ups
- Bisphosphonate medications — to protect bone strength
- Early treatment — especially for high-risk SMM, sometimes using medications like Revlimid (lenalidomide)
It's always worth discussing with your doctor which approach is right for your specific situation.
October 17
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