Yes!! The high dose dexamethasone can raise our blood pressure cholesterol and lipids. My blood pressure went up on Kyprolis. Pomalyst can also raise blood pressure.
September 28
Yes, induction therapy for myeloma can contribute to low blood pressure, though it's not always listed as a primary side effect. The medications involved can affect the body in ways that may lead to drops in blood pressure.
Here are some ways induction therapy drugs may play a role:
- Corticosteroids (like dexamethasone) can Show Full Answer
Yes, induction therapy for myeloma can contribute to low blood pressure, though it's not always listed as a primary side effect. The medications involved can affect the body in ways that may lead to drops in blood pressure.
Here are some ways induction therapy drugs may play a role:
- Corticosteroids (like dexamethasone) can cause fluid and electrolyte imbalances, which may affect blood pressure
- Proteasome inhibitors (like bortezomib/Velcade) are known to sometimes cause low blood pressure as a side effect
- Immunomodulatory drugs (like lenalidomide/Revlimid) can also contribute to cardiovascular changes
It's worth noting that dehydration from side effects like diarrhea or nausea — which are common during induction therapy — can also cause blood pressure to drop. If low blood pressure is being experienced during induction therapy, it's really important to flag this with the oncology team right away. They can adjust medications or recommend ways to manage it safely. Don't try to manage it alone — this one definitely needs a professional's eyes on it.
September 28
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