Has anyone had this reaction on Darcelex. Right now I need to get an Endoscopy again to rule out the Amyloid and a second bone marrow biopsy to see if I have gone to full MM. My wbc count went down very low but now is up to 2.3. My scalp is very itchy but not red.
Mary, I am very sorry this happened to you. I've been on Darzalex since October of 2017. I do get diarrhea for a day afterwards TMI, but nothing like you describe. I also have a low white count. But it's borderline, usually not low enough to hold my treatment. I also take Pomalyst which I blame as the culprit for my low wbc's.. It's probably both! I also get the horrible, crawly itchy scalp. I have to wash my hair every night after I take my Pomalyst. I hope they find out the cause of your low counts. My counts were very low due to my myeloma. Darzalex has actually been a godsend for me.
It sounds like there are a few side effects happening at once — that's a lot to deal with, and it's worth breaking each one down.
Low White Blood Cell Count (Neutropenia)
This is a known and serious side effect of Darzalex. Lower white blood cell counts mean a higher risk of infection, so it's really important to: