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Real members of MyMyelomaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

I take a shot of Daratumumab once a month. One other prescribed med, acyoclivar twice a day. Is it inevitable that my progression will worsen at some point?

September 2
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A MyMyelomaTeam Member

Thanks for quick reply. Seems there are a lot of different diagnosis’s in handling this thing.

September 2
MyMyelomaTeam

Welcome! It's great that you're experiencing no side effects from your monthly daratumumab injection — that's genuinely good news, and not something to feel suspicious about. Everyone responds differently to treatment, and some people tolerate daratumumab very well.

Daratumumab works by targeting a specific protein on Show Full Answer

Welcome! It's great that you're experiencing no side effects from your monthly daratumumab injection — that's genuinely good news, and not something to feel suspicious about. Everyone responds differently to treatment, and some people tolerate daratumumab very well.

Daratumumab works by targeting a specific protein on myeloma cells, helping your immune system identify and attack them. The most common side effects some people do experience include:

- Fatigue
- Nausea
- Back pain
- Fever or cough
- Low blood cell counts

The fact that you're not experiencing these is a win, not a warning sign! As for progression — it's a fair and important question. Myeloma does have a tendency to relapse over time for most people, meaning it can return after a period of responding well to treatment. Some people do remain stable for long periods though.

The encouraging news is that treatment options have expanded significantly. Newer combinations and therapies are showing strong results, so if your myeloma ever does change course, there are more tools available than ever before.

The best person to discuss your individual outlook with is your specialist, who knows your specific case in detail.

September 2

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