Yes, muscle spasms in the legs can absolutely be a side effect of induction therapy for myeloma. It's a frustrating but common experience that many people go through during treatment. There are a few reasons why this can happen:
- Chemotherapy-induced peripheral neuropathy (CIPN): Some chemo drugs can damage nerves outside Show Full Answer
Yes, muscle spasms in the legs can absolutely be a side effect of induction therapy for myeloma. It's a frustrating but common experience that many people go through during treatment. There are a few reasons why this can happen:
- Chemotherapy-induced peripheral neuropathy (CIPN): Some chemo drugs can damage nerves outside the brain, particularly in the hands and feet, leading to tingling, numbness, and muscle spasms
- Immunomodulatory drugs: These medications, often used alongside chemo, can affect muscle tissue and the central nervous system, sometimes triggering spasms
- Electrolyte imbalances: Myeloma and its treatments can disrupt levels of magnesium, potassium, and calcium in the blood, which can cause cramping
- Hypercalcemia: Elevated calcium levels in the blood, which myeloma can cause, is another known trigger for muscle cramps One MyMyelomaTeam member shared that after their oncologist adjusted their treatment plan, the severe cramps in their legs, feet, and hands almost completely went away. They also found that taking electrolytes and magnesium citrate helped.
It's really worth bringing this up with your oncology team. They may check your blood for mineral deficiencies or review your medications. Possible approaches to relief can include:
- Staying well hydrated
- Stretching cramped muscles
- Magnesium or potassium supplements (under doctor guidance)
- Muscle relaxants in some cases
- Acupuncture or other complementary therapies
August 27
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