Letitia,
The Multiple Myeloma Research Foundation emailed me the article this morning. It’s a new drug for those whose treatments have failed many times. You should get on their email list. HTTPS://www.themmrf.org
Paula🌹
Clinical trial results from the pivotal phase 3 EXCALIBER-RRMM trial showed that iberdomide combined with daratumumab and dexamethasone (IberDd) achieved a 41% minimal residual disease (MRD)-negative complete response rate at any time, compared to 21% for the standard comparator arm containing daratumumab, bortezomib, and dexamethasone (P < 0.0001). This deep molecular response formed the primary basis for the FDA's accelerated approval.
Letitia,
Go back to Q & A so more people can see your question.💕
Paula🌹
I was informed Iberdomide (brand name Zenbexus) is an oral cereblon E3 ligase modulator (CELMoD) approved by the U.S. FDA in August 2026. It is used with daratumumab and dexamethasone to treat adults with relapsed or refractory multiple myeloma who have received at least one prior therapy.
Has anyone heard about this new drug and has anyone started this new drug ?
That link leads to a Facebook video, but it's not possible to access or view external links or social media content directly.
If you can share what the news was about, it would be much easier to help figure out if it's relevant to myeloma and whether it's worth paying attention to. Sometimes health news shared on social Show Full Answer