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22K views · 2.6K reactions | #cancer The FDA approved iberdomide, a CELMoD class pill, in combination with daratumumab/dexamethasone in adults with multiple myeloma who have received at least one prior line of therapy. There was significantly improved minimal residual disease rates. | Blooddocdad
22K views · 2.6K reactions | #cancer The FDA approved iberdomide, a CELMoD class pill, in combination with daratumumab/dexamethasone in adults with multiple myeloma who have received at least one prior line of therapy. There was significantly improved minimal residual disease rates. | Blooddocdad
August 14
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A MyMyelomaTeam Member

Letitia,
The Multiple Myeloma Research Foundation emailed me the article this morning. It’s a new drug for those whose treatments have failed many times. You should get on their email list. HTTPS://www.themmrf.org
Paula🌹

The MMRF | Multiple Myeloma Research Foundation
The MMRF | Multiple Myeloma Research Foundation
August 14
A MyMyelomaTeam Member

Clinical trial results from the pivotal phase 3 EXCALIBER-RRMM trial showed that iberdomide combined with daratumumab and dexamethasone (IberDd) achieved a 41% minimal residual disease (MRD)-negative complete response rate at any time, compared to 21% for the standard comparator arm containing daratumumab, bortezomib, and dexamethasone (P < 0.0001). This deep molecular response formed the primary basis for the FDA's accelerated approval.

August 14
A MyMyelomaTeam Member

Letitia,
Go back to Q & A so more people can see your question.💕
Paula🌹

August 18
A MyMyelomaTeam Member

I was informed Iberdomide (brand name Zenbexus) is an oral cereblon E3 ligase modulator (CELMoD) approved by the U.S. FDA in August 2026. It is used with daratumumab and dexamethasone to treat adults with relapsed or refractory multiple myeloma who have received at least one prior therapy.

Has anyone heard about this new drug and has anyone started this new drug ?

August 17
MyMyelomaTeam

That link leads to a Facebook video, but it's not possible to access or view external links or social media content directly.

If you can share what the news was about, it would be much easier to help figure out if it's relevant to myeloma and whether it's worth paying attention to. Sometimes health news shared on social Show Full Answer

That link leads to a Facebook video, but it's not possible to access or view external links or social media content directly.

If you can share what the news was about, it would be much easier to help figure out if it's relevant to myeloma and whether it's worth paying attention to. Sometimes health news shared on social media can be exciting but needs a closer look before getting too hopeful (or worried!).

August 14

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