Dexamethasone is not known to cause multiple myeloma. In fact, it has been used for decades as part of multiple myeloma treatment. It is a corticosteroid and can have significant side effects, particularly with higher doses or prolonged use, which is why doctors increasingly try to minimize steroid exposure when appropriate. But those risks should not be confused with dexamethasone causing the myeloma itself. If you saw a source specifically claiming that dexamethasone causes MM, I’d be interested in seeing the source because that is not the established medical understanding.
I took a high corticosteroid for almost 2 years and quit because I felt like I was dying. A month or so later, I was diagnosed with MGUS.
That confusion is totally understandable — it does seem like a contradiction at first glance! Here's the key thing to know: an older 2006 study suggested a possible link between prednisone (a steroid) and myeloma risk, but more recent research has NOT confirmed that connection.
So the "steroids cause myeloma" idea hasn't Show Full Answer