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Real members of MyMyelomaTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
August 5
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A MyMyelomaTeam Member

With what limited knowledge I have access to (or for what it’s worth) yes , yeast infections can occur during myeloma treatment because several of these medications can suppress the immune system. Dexamethasone can be particularly relevant because steroids both suppress immunity and can raise blood sugar, which can encourage yeast growth. Daratumumab, Revlimid and venetoclax can also increase susceptibility to infections in different ways.

IVIG is generally given to help reduce infection risk when antibody levels are low, so I would not automatically assume the IVIG itself is causing it simply because the symptoms appear afterward.

Since yours seems to recur after treatment, I would mention the timing to your oncology team. They may want to confirm that it really is Candida, check blood counts and glucose, and decide whether treatment or prevention is appropriate rather than repeatedly treating it on your own.

August 11
A MyMyelomaTeam Member

Just Google Uri Shah MSK Nutrivention Study.

August 9
A MyMyelomaTeam Member

Thats exactly the soap i use! How do i find uri shas info

August 5
A MyMyelomaTeam Member

It's a side effect of a bad gut or skin microbiome. Check out Uri Shah's webinars on healthy gut foods to help our immunity through a healthy gut. Also use a mild soap like Dove sensitive. 🥰

August 5
MyMyelomaTeam

That's a really important question, and it makes sense to connect the dots between your treatments and what your body is experiencing.

Yeast infections aren't always listed as a direct named side effect of Revlimid (lenalidomide), daratumumab (Dara), or dexamethasone (Dex), but they are very much linked to how these Show Full Answer

That's a really important question, and it makes sense to connect the dots between your treatments and what your body is experiencing.

Yeast infections aren't always listed as a direct named side effect of Revlimid (lenalidomide), daratumumab (Dara), or dexamethasone (Dex), but they are very much linked to how these treatments affect your immune system.

Here's why they can happen:

- Revlimid is an immunomodulatory drug that increases your overall infection risk
- Dexamethasone is a steroid that suppresses the immune system, making it harder to fight off fungal overgrowth like yeast
- Daratumumab can lower certain white blood cell counts, reducing your ability to fight infections

When your immune defenses are lowered by these treatments, yeast (which naturally lives in the body) can overgrow more easily — especially around infusion time when your body is under extra stress. It's really worth mentioning this pattern to your care team, especially since it seems to happen consistently after your Dara and IgG infusion. They may be able to offer a preventative antifungal option or other strategies to help manage it. Don't brush it off as minor — recurring infections, even mild ones, are worth tracking and reporting.

August 5

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