MyMyelomaTeam

Great question. Research does show a link between hepatitis B (HBV) and hepatitis C (HCV) and higher rates of both MGUS and multiple myeloma. Since smoldering myeloma (SMM) sits between MGUS and active myeloma on the spectrum of plasma cell disorders, hepatitis viruses may play a role in its development too. Here's what's Show Full Answer

Great question. Research does show a link between hepatitis B (HBV) and hepatitis C (HCV) and higher rates of both MGUS and multiple myeloma. Since smoldering myeloma (SMM) sits between MGUS and active myeloma on the spectrum of plasma cell disorders, hepatitis viruses may play a role in its development too. Here's what's currently understood about the connection:

- Hepatitis viruses may weaken the immune system and disrupt normal cell growth, which could contribute to abnormal plasma cell activity
- People with HBV and HCV have been found to have higher rates of MGUS, which is the precursor to SMM
- The good news is that antiviral therapy for hepatitis has been shown to improve myeloma outcomes, suggesting treating the virus early may help

If there's a history of hepatitis, it's really worth raising this with an oncology team. Early monitoring and treatment can make a meaningful difference.

 AI-generated responses are not a substitute for medical advice. These services are not intended to diagnose, treat, or cure any condition or disease. Always ask your doctor about specific health concerns.

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