Yes, several myeloma treatments can increase the risk of blood clots. This is an important thing to be aware of, so here's a breakdown:
Immunomodulatory drugs (IMiDs) — these carry one of the highest risks, especially when combined with other treatments
- Thalidomide (Thalomid)
- Lenalidomide (Revlimid)
- Pomalidomide Show Full Answer
Yes, several myeloma treatments can increase the risk of blood clots. This is an important thing to be aware of, so here's a breakdown:
Immunomodulatory drugs (IMiDs) — these carry one of the highest risks, especially when combined with other treatments:
- Thalidomide (Thalomid)
- Lenalidomide (Revlimid)
- Pomalidomide (Pomalyst)
Taking any of these alongside dexamethasone can make someone six times more likely to develop a blood clot. Proteasome inhibitors can also raise clot risk:
- Bortezomib (Velcade)
- Carfilzomib (Kyprolis)
- Ixazomib (Ninlaro)
Other treatments and procedures linked to increased clot risk include:
- Chemotherapy and radiation therapy
- Stem cell transplants (both autologous and allogeneic)
- IV catheters or ports
- High-dose dexamethasone (160mg or more) It's really worth discussing clot prevention with the care team, especially if on any of these treatments. Doctors often recommend blood thinners, compression stockings, staying hydrated, and keeping active as preventive measures. If any symptoms like chest pain, shortness of breath, or leg swelling appear, seek medical attention right away.
July 20
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