Yes, it is possible. While abnormal protein levels (like M protein) are a common marker of myeloma, they aren't the only way the condition is identified. Some people with myeloma may not produce detectable M protein — this is sometimes called "non-secretory" myeloma.
Doctors look at a combination of factors to diagnose Show Full Answer
Yes, it is possible. While abnormal protein levels (like M protein) are a common marker of myeloma, they aren't the only way the condition is identified. Some people with myeloma may not produce detectable M protein — this is sometimes called "non-secretory" myeloma.
Doctors look at a combination of factors to diagnose myeloma, not just protein levels. These can include:
- Bone marrow biopsy results (checking for abnormal plasma cells)
- Imaging tests (looking for bone lesions or tumors)
- Blood calcium levels
- Kidney function
- Red blood cell levels (checking for anemia)
- Genetic changes in myeloma cells It's always worth having an open conversation with a specialist about all test results together, rather than focusing on any single marker. A hematologist or oncologist experienced in myeloma can give the clearest picture of what the results mean for each individual situation.
June 30
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