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May 31
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Being diagnosed with MGUS and placed on a "watch and wait" approach with yearly check-ups is actually very common — so you're definitely not alone in this situation.

MGUS affects around 2–3% of people over 50, and that number rises to about 5% in those over 70. Many people with MGUS never need treatment and simply stay on a Show Full Answer

Being diagnosed with MGUS and placed on a "watch and wait" approach with yearly check-ups is actually very common — so you're definitely not alone in this situation.

MGUS affects around 2–3% of people over 50, and that number rises to about 5% in those over 70. Many people with MGUS never need treatment and simply stay on a monitoring plan like yours. Having two M protein bands (IgG and IgA) along with an abnormal Kappa/Lambda ratio does mean your care team will want to keep a close eye on things. The abnormal free light chain ratio is considered a risk factor for progression, which is likely why regular monitoring has been recommended.

Here are some symptoms worth watching for between check-ups:

- Bone pain
- Unusual tiredness
- Unexplained weight loss
- Nerve pain or tingling
- Night sweats
- Unexplained bleeding or bruising The good news is that yearly follow-ups are standard for lower-risk MGUS, and most people go many years without any progression. Staying consistent with those appointments is really the most important thing right now.

May 31

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